BDBM466916 1-(3-{6-[(3R)-3- Methylmorpholin-4-yl]-2- {1H-pyrrolo[2,3-b]pyridin-4- yl}pyrimidin-4-yl}piperidin- 1-yl) ethan-1-one::US10800774, Example 15
SMILES C[C@@H]1COCCN1c1cc(nc(n1)-c1ccnc2[nH]ccc12)C1CCCN(C1)C(C)=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 466916
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 210nMAssay Description:Inhibitors of ATR kinase are effective at inhibiting the ATR-driven phosphorylation of the downstream target Chk1 kinase at Serine 345, following the...More data for this Ligand-Target Pair